Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Rat Interferon-gamma (Rat IFN-γ)
                
                

                
91216ES60
                
                

                
100 μg
                
                

                
1855.00
                
            
            

                

                
91216ES76
                
                

                
500 μg
                
                

                
7495.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a pleiotropic cytokine which is now recognised as an important modulator of the immune response. Mature human IFN-γ exists as a non-covalently linked homodimer of 20-25 kDa variably glycosylated subunits. It shares 90% amino acid (aa) sequence identity with rhesus IFN-γ, 59%64% with bovine, canine, equine, feline, and porcine IFN-γ, and 37%43% with cotton rat, mouse, and rat IFN-γ. Interferons have had increasing clinical usage in the treatment of a variety of disorders, at times being used in combination with chemo\ or radiotherapy. IFN-γ increases the potential immunogenicity of vascular endothelial cells by up-regulation of intercellular adhesion molecule-1 (ICAM-1) and class I MHC antigen expression and by induction of class II MHC antigens and certain chemokines.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
Interferon-gamma, IFN-γ, IFG, IFI, IFNG, IFNgamma, IFN-gamma.
                
            
            

                

                
Accession
                
                

                
P01581
                
            
            

                

                
GeneID
                
                

                
25712
                
            
            

                

                
Source
                
                

                
E.coli-derived rat IFN-γ protein, Gln23-Cys156.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 15.5 kDa.
                
            
            

                

                
AA Sequence
                
                

                
QGTLIESLES LKNYFNSSSM DAMEGKSLLL DIWRNWQKDG NTKILESQII SFYLRLFEVL KDNQAISNNI SVIESHLITN FFSNSKAKKD AFMSIAKFEV NNPQIQHKAV NELIRVIHQL SPESSLRKRK RSRC
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
> 97% by SDS-PAGE and HPLC analyses.
                
            
            

                

                
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