Monoclonal Antibody against a Calcium Dependent Activation Epitope on Integrin β1
产品名称： Monoclonal Antibody against a Calcium Dependent Activation Epitope on Integrin β1
英文名称： Monoclonal Antibody against a Calcium Dependent Activation Epitope on Integrin β1
产品编号： MMS-480R
产品价格： null
产品产地： USA
品牌商标： COVANCE
更新时间： 2024-12-10T13:18:22
使用范围：
翌圣生物科技（上海）股份有限公司
- 联系人 : 李自转
- 地址 : 上海市浦东新区天雄路166弄一号楼三层南单元
- 邮编 : 200030
- 所在区域 : 上海
- 电话 : 139****5640 点击查看
- 传真 : 点击查看
- 邮箱 : lizizhuan@yeasen.com
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| Description |  |
Monoclonal Antibody against a Calcium Dependent Activation Epitope on Integrin β1 |
| Intended Use | |
**Research Use Only (RUO)** This product is sold for laboratory research use only, not for human or in-vivo use. |
| Clone | |
P4G11 |
| Form | |
Ascites |
| Host | |
Mouse |
| Species Reactivity | |
Human |
| IsoType | |
IgG1 |
| [Ab] | |
2-3 mg/mL |
| Specificity | |
The P4G11 monoclonal antibody was generated against IL-1β activated human umbilical vein endothelial cells (HUVECs). P4G11, reacts with calcium-dependent epitopes on the integrin β1 subunit. When bound to β1, P4G11, activates β1 dependent binding to extra cellular matrix substrates. |
| Uses | |
This antibody is effective in immunoblotting, immunofluorescence (IF) and immunoprecipitation (IP). |
| Suggested Working Dilution | |
The optimal working dilution should be determined for each specific assay condition.
|
| Storage | |
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. For long-term storage, keep the antibody at -80°C. |
| References | |
Wayner EA, Hoffstrom BG. Monoclonal antibodies to integrin receptors. Meths. Enzymol. In: Integrins, edited by David Cheresh, 426:117-154, 2007. [General Use] Wayner EA, Gil SG, Murphy GF, Wilke MS, Carter WG. Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes. J Cell Biol 121(5):1141-1152, 1993. [IP] |
| Warranty/Conditions | |
Covance products may not be resold or modified for resale without prior written approval. |
| Rev. Date | |
3/3/2009 |