FITC标记的核孔复合蛋白Nup133抗体
产品名称： FITC标记的核孔复合蛋白Nup133抗体
英文名称： Anti-NUP133/FITC
产品编号： HZ-19542R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NUP133/FITC Conjugated antibody
FITC标记的核孔复合蛋白Nup133抗体
| 英文名称 | Anti-NUP133/FITC |
| 中文名称 | FITC标记的核孔复合蛋白Nup133抗体 |
| 别 名 | 133 kDa nucleoporin; FLJ10814; hNUP 133; hNUP133; MGC21133; NU133_HUMAN; Nuclear pore complex protein Nup133; Nucleoporin 133kDa; Nucleoporin NUP133; NUP 133; NUP133; OTTHUMP00000061095. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 129kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NUP133 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. [provided by RefSeq, Jul 2008] Subcellular Location: Nucleus > nuclear pore complex. Chromosome > centromere > kinetochore. Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores. Tissue Specificity: Involved in poly(A)+ RNA transport. Similarity: Belongs to the nucleoporin Nup133 family. Database links: Entrez Gene: 55746 Human Omim: 607613 Human SwissProt: Q8WUM0 Human Unigene: 12457 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
核膜在真核细胞中产生明显的细胞核和细胞质室。它由两个被核孔穿孔的同心膜组成，大蛋白复合物形成水通道以调节大分子在核和细胞质之间的流动。这些复合物由至少100种不同的多肽亚基组成，其中多个属于核孔蛋白家族。由该基因编码的核孔蛋白显示与其他核孔蛋白的进化保守的相互作用。这种蛋白质在间期定位于核孔复合体的两侧，在有丝分裂期间仍与该复合体相关联，并且靶向于重组核包膜的早期阶段。这种蛋白质也定位于有丝分裂细胞的着丝粒。[ RefSeq，JUL 2008 ]