FITC标记的细胞酪氨酸转氨酶抗体
产品名称： FITC标记的细胞酪氨酸转氨酶抗体
英文名称： Anti-ATTY/FITC
产品编号： HZ-1907R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-ATTY/FITC Conjugated antibody
FITC标记的细胞酪氨酸转氨酶抗体
| 英文名称 | Anti-ATTY/FITC |
| 中文名称 | FITC标记的细胞酪氨酸转氨酶抗体 |
| 别 名 | TYROSINE AMINOTRANSFERASE; tyrosine aminotransferase; MGC37772; MGC37789; MGC37790; MGC37819; MGC37828; MGC37842; TAT; ATTY_HUMAN; L-tyrosine:2-oxoglutarate aminotransferase; TAT; Tyrosine aminotransferase; Tyrosine aminotransferase, cytosolic. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 激酶和磷酸酶 合成与降解 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Tat |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked. Function: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has no transaminase activity towards phenylalanine. Subunit: Homodimer (Probable). DISEASE: Defects in TAT are the cause of tyrosinemia type 2 (TYRO2) [MIM:276600]; also known as Richner-Hanhart syndrome. TYRO2 is an inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, and oculocutaneous manifestations. Typical features include palmoplantar keratosis, painful corneal ulcers, and mental retardation. Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Database links: Entrez Gene: 6898 Human Entrez Gene: 234724 Mouse Entrez Gene: 24813 Rat Omim: 613018 Human SwissProt: P17735 Human SwissProt: Q8QZR1 Mouse SwissProt: P04694 Rat Unigene: 161640 Human Unigene: 28110 Mouse Unigene: 9947 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该核基因编码线粒体蛋白酪氨酸氨基转移酶，其存在于肝脏中，并催化L-酪氨酸转化成对羟基丙酮酸。该基因的突变导致酪氨酸血症（II型，Rijner-Hhanar综合征），伴随着主要皮肤和角膜病变的一种病症，可能伴有精神发育迟滞。酪氨酸转氨酶的调节基因是X连锁的。